Note published: News @ the University of Toronto, Melissa McDermott, 08/09/1914. "Researches discover the first-ever link entre intelligence and curiosity"
pimer Researchers discover link between intelligence and curiosity: The results may lead to development of drugs that enhance learning.
In an article published Sept. 10 in the respected journal Neuron, Professor John Roder, University of Toronto, Department of Molecular Genetics and Fellow in the Lunenfield and Bechara Saab doctoral student at the same institute investigated the interaction of two proteins in the region of the brain called the dentate gyrus (one of the three parts of the hippocampus, which plays an important role in long-term memory and spatial coordination).
"Dr Roder and Bechara Saab have made important discoveries in a brain region that has been poorly studied in the past," said Dr. Jim Woodgett, Director at the Lunenfeld. "The relationship molecular discovery holds promise for the future of cognitive therapy."
The study was developed in collaboration with other scientists Toronto and Switzerland. It is also funded by the Canadian Institutes of Health Research.
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original Note: http://www.news.utoronto.ca/lead-stories/researchers-discover-the-firstever-link-between-intelligence-and -curiosity.html "Dr Roder and Bechara Saab have made important discoveries in a brain region that has been poorly studied in the past," said Dr. Jim Woodgett, Director at the Lunenfeld. "The relationship molecular discovery holds promise for the future of cognitive therapy."
Particularly in the study, the neuronal calcium receptor-1 (NCS-1), a protein known to affect memory in worms and is associated with bipolar disorder and schizophrenia in people, increased its activity one and a half times in the dentate gyrus in mice. This slight overexpression increased the ability of brain cells to change the way we communicate, and in mice caused an increase in upper memory to perform complex tasks and a significant increase in exploratory behavior, ie the curiosity.
Since exploratory behavior is modified only in a "safe", the investigadorescreen they have discovered a brain region that creates curiosity, and a model that explains how brain activity leads to curiosity. They also discovered that curiosity and spatial memory are altered when given a benign drug that blocks the binding protein NCS-1 dela with dopamine receptor type 2 (primary target of antipsychotics) in the dentate gyrus. "We now know that some of the molecules and brain regions that regulate learning and memory also control curiosity, we can now develop drugs laboratory that improve cognition in humans - which means a potential benefit for the future" said Saab. "However, we can immediately put into practice the knowledge generated indicating that the building encourages curiosity, intelligence, and vice versa."
Since exploratory behavior is modified only in a "safe", the investigadorescreen they have discovered a brain region that creates curiosity, and a model that explains how brain activity leads to curiosity. They also discovered that curiosity and spatial memory are altered when given a benign drug that blocks the binding protein NCS-1 dela with dopamine receptor type 2 (primary target of antipsychotics) in the dentate gyrus. "We now know that some of the molecules and brain regions that regulate learning and memory also control curiosity, we can now develop drugs laboratory that improve cognition in humans - which means a potential benefit for the future" said Saab. "However, we can immediately put into practice the knowledge generated indicating that the building encourages curiosity, intelligence, and vice versa."
The study was developed in collaboration with other scientists Toronto and Switzerland. It is also funded by the Canadian Institutes of Health Research.
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